1. 3D Printing Of Organs

Organ transplantation using 3D-printed hearts, lungs, livers and kidneys? Thanks to additive manufacturing (i.e., 3D printing), this is now possible, although not currently practical or practicable. That said, current developments in bioprinting hint at a seemingly endless well of possibilities for 3D-printed organ and tissue transplantation.

Different organizations specializing in bioprinting research and development have experienced varying success rates in 3D printing organs and human tissue.

Researchers from the Israel Institute of Technology, for instance, reported successfully engineering tissue flaps with a bioprinted blood vessel network.

The scientists and engineers from the Wake Forest Institute for Regenerative Medicine have also printed and implanted animal ear, bone and muscle structures, which developed blood vessel systems and matured into functional tissue. The Institute is also working on skin-printing technology that will hopefully allow medical practitioners to print skin on demand directly onto a patient’s burn or wound.

The world is a long way off from getting 3D-printed organs approved for human use, mainly due to the challenge of printing organs with all the required cell types that will work and continue to work as they must after transplantation into a host. Nonetheless, we can rest assured that real progress is being made on this front.

2. Custom Manufacturing Of Medical Devices

3D printing already has a place in medical device prototyping, an essential step in device manufacturing workflows.

Translating a concept into something tangible helps validate and prove conceptual designs. In the long run, it helps minimize errors that can lead to costly product recalls, not to mention damage to brand reputation. In medical device manufacturing, prototyping can be particularly vital, seeing as some devices can mean the difference between life and death for patients.

Beyond rapid prototyping, 3D printing’s other applications in medical device manufacturing include:

• Creating the tools, models, molds, casts and patterns necessary for traditional manufacturing; e.g., the vacuum forming models used in the manufacture of dental aligners and retainers
• Printing custom-designed, single-use, sterile surgical instruments; e.g., extra-tiny surgical instruments for operating on small areas, printed on demand at a cost lower than if they were produced using subtractive or traditional manufacturing methods and not requiring sterilization and storage
• Manufacturing end-use medical parts and devices; e.g., 3D product development means innovative-design and low-cost inhalers and portable metabolic analyzers
• Printing emergency-use medical devices; e.g., bi-level positive airway pressure (BiPAP) adapters

3. Made-To-Order Prosthetics

Prostheses are artificially constructed devices made to restore a specific body part’s function or appearance. When envisioning prosthetic devices, you probably think immediately of artificial limbs.

The field of prostheses encompasses more than artificial hands, legs and fingers. It also includes hearing aids, dentures, ceramic crowns and dental plates.

Prosthetic implants must be tailored to their wearer for a snug, comfortable and wearable fit. A customized design also ensures the prosthetic device does not look out of place. Dentures, for instance, need to be sized appropriately to ensure they won’t drastically alter the wearer’s facial features.

3D printing is particularly apt for manufacturing custom prosthetic devices. A medical prosthetics manufacturer can scan a patient’s limb’s shape and size to create custom limb prosthetics. Dental service providers can also use 3D printing to make dental crowns that mimic the teeth’s natural occlusion.

4. Medical Models For Research And Training

Even if we’re far from 3D-printed organ transplantation, bioprinting means tremendous advances in the field of medical research and training. Through 3D printing, medical researchers can print models of human organs that they can use for experimentation and surgical simulation.

The following bioprinted medical models are outcomes of 3D printing:

• In-vitro retina model for studying age-related macular degeneration (AMD), retinitis pigmentosa (RP), and other such diseases
• Blood vessel model for studying vascular diseases and to support cardiovascular drug research
• Full-size human heart model that mimics the elasticity of heart tissue for surgery planning and realistic surgery practice
• Optical tissue phantoms for medical device calibration and equipment validation

3D Printing: Expanding The Realm Of Medical Possibilities

3D printing has extensive applications in manufacturing medical devices, custom prostheses and emergency supplies. Through bioprinted organ and tissue models, 3D printing also paves the way for advanced medical training, research and innovation.

As 3D printing technology develops and our knowledge of the human anatomy broadens, 3D printing organs for human transplantation will soon move beyond possibility into the realm of reality.

Proto21 is a market leader in 3D printing in the Middle East. We provide 3D scanning, design and printing services as well as 3D product development, painting and finishing services.

Talk to us if you need 3D printing, modeling and manufacturing expertise.
Email: info@proto21.ae
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